HCID 14647076, compound → HCID 136381075, compound

HRID 1451163Notes

Reaction equation

HRID 1451163 reaction equation
[OH:1][C:2]1[CH2:7][CH:6]([C:8]2([S:11][CH3:12])[CH2:10][CH2:9]2)[CH2:5][C:4](=[O:13])[C:3]=1[C:14](=O)[CH2:15][CH3:16].[Cl:18][C:19]1[CH:24]=[CH:23][C:22](/[CH:25]=[CH:26]/[CH2:27][CH2:28][O:29][NH2:30])=[CH:21][CH:20]=1>CO>[Cl:18][C:19]1[CH:20]=[CH:21][C:22](/[CH:25]=[CH:26]/[CH2:27][CH2:28][O:29][N:30]=[C:14]([C:3]2[C:4](=[O:13])[CH2:5][CH:6]([C:8]3([S:11][CH3:12])[CH2:10][CH2:9]3)[CH2:7][C:2]=2[OH:1])[CH2:15][CH3:16])=[CH:23][CH:24]=1

Participants

4

Reactant 2

HCID 14647076HCID 14647076, compoundHCID 178458887HCID 178458887, compound

Product 1

HCID 136381075HCID 136381075, compoundYield 100%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 2.0 g (7.9 mmol) of 3-hydroxy-5-(1-methylthiocyclopropyl)-2-propionyl-2-cyclohexen-1-one, 1.8 g (9.0 mmol) of O-[4-trans-(4-chlorophenyl)-but-3-enyl]-hydroxylamine and 100 ml of methanol was stirred for 24 hours and then evaporated down under reduced pressure. Yield: 100%

Workup

  1. customevaporated down under reduced pressure

Sources & evidence

ORD record
ord-27439b0020a34633acf5c66e9d692632
Source dataset
uspto-grants-1997_02
Patent number
US05604183

Reaction notes

Loading…