反应详情

A 30% ammonium hydroxide solution (56 mL) is added dropwise to a solution of 2-bromo-5-methoxybenzoyl chloride in methylene chloride at 0° C. After the addition is complete, the reaction mixture is filtered to obtain a solid which is air-dried and recrystallized from a methanol/water solution to give the title product as a white solid, mp 158°-159° C.

1. additionAfter the addition
2. filtrationthe reaction mixture is filtered
3. customto obtain a solid which
4. customis air-dried
5. customrecrystallized from a methanol/water solution