Diethylamine → HCID 19040717, compound

HRID 1451271Notes

Reaction equation

HRID 1451271 reaction equation
Cl[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[C:18]3[CH:19]=[C:20]4[O:25][CH2:24][O:23][C:21]4=[CH:22][C:17]=3[CH2:16][C:15]([CH3:26])=[N:14][N:13]=2)=[CH:8][CH:7]=1)=[O:4].[CH2:27]([NH:29][CH2:30][CH3:31])[CH3:28]>>[CH2:27]([N:29]([CH2:30][CH3:31])[CH2:2][C:3]([NH:5][C:6]1[CH:11]=[CH:10][C:9]([C:12]2[C:18]3[CH:19]=[C:20]4[O:25][CH2:24][O:23][C:21]4=[CH:22][C:17]=3[CH2:16][C:15]([CH3:26])=[N:14][N:13]=2)=[CH:8][CH:7]=1)=[O:4])[CH3:28]

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 54255983HCID 54255983, compound

Product 1

HCID 19040717HCID 19040717, compound

Procedure

It was prepared from 1-(4-chloroacetylaminophenyl)-4-methy1-7,8-methylenedioxy-5H-2,3-benzodiazepine by using the process of Example 102, except that diethylamine was used instead of pyrrolidine, m.p.: 157°-158° C.

Sources & evidence

ORD record
ord-6b231eae72fb4bf89715328aaf84efb9
Source dataset
uspto-grants-1997_02
Patent number
US05604223

Reaction notes

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