Benzyl Bromide → HCID 178419390, compound

HRID 1451354Notes

Reaction equation

HRID 1451354 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH:14]=[CH:13][N:12]=[C:11]2[CH:15]2[O:19][CH2:18][CH2:17][O:16]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:20]([Br:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[Br-:27].[CH2:20]([N:12]1[CH:13]=[CH:14][N+:10]([CH2:9][CH2:8][CH2:7][C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[C:11]1[CH:15]1[O:16][CH2:17][CH2:18][O:19]1)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 19974087HCID 19974087, compound

Product 1

HCID 178419390HCID 178419390, compoundYield 87%

Procedure

A reaction mixture of 18 g (70 mmol) of 1-(3-phenylpropyl)-2-(1,3-dioxolan-2-yl)imidazole and 11.93 g (70 mmol) of benzyl bromide was stirred at room temperature for 8 h. The mixture was triturated with ethyl acetate, decanted and dried to afford 26.1 g (87%) of 3-benzyl-2-(1,3-dioxolan-2-yl)-1-(3-phenylpropyl)imidazolium bromide (Formula VI: A=1-(3-phenylpropyl)imidazole; Y=2-(1,3-dioxolan-2-yl; R1 =R6 =H; Z- =Br-).

Workup

  1. customThe mixture was triturated with ethyl acetate
  2. customdecanted
  3. customdried

Sources & evidence

ORD record
ord-b1901bc26bb74c5889c199a530eee827
Source dataset
uspto-grants-1997_02
Patent number
US05604224

Reaction notes

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