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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1451418Generated: October 27, 2026

Methyl 2-(4-(2-oxopropyl)phenoxy)acetate → N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(thiazol-4-yl)ethanamine

https://huagongshe.com/reaction/1451418

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(4-(2-oxopropyl)phenoxy)acetateHCID 13851156—
Reactant2-Amino-1-(thiazol-4-yl)ethanolHCID 19974168—
ProductN-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(thiazol-4-yl)ethanamineHCID 19974207—

Reaction Steps

Prepared analogously to Example 13 by reaction of 2-hydroxy-2-(thiazol-4-yl)ethylamine with 1-(4-carbomethoxymethoxyphenyl)propan-2-one followed by purification of the base on a silica gel column using ethyl acetate/methanol=8:2 as eluant.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05604225
Source datasetuspto-grants-1997_02
ORD IDord-aa2ec2526c974f63bbe70a63311e1d5d
Source noteuspto-grants-1997_02