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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1451470Generated: October 31, 2026

Potassium Bicarbonate → HCID 14347783, compound

https://huagongshe.com/reaction/1451470

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium BicarbonateHCID 516893—
ReactantHCID 10978660HCID 10978660—
ReactantN-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamineHCID 14347763—
ReactantHCID 14347785HCID 14347785—
SolventAcetoneHCID 180—
ProductHCID 14347783HCID 14347783—

Reaction Steps

N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2,6-bis(2-trifluoromethyl-thiazol-4-yl)morpholine from N-[2-(4-carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethyl-thiazol-4-yl)ethanamine (pair of diastereomers A) with 2-trifluoromethyl-4-bromoacetyl-thiazole and potassium hydrogen carbonate in acetone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05604225
Source datasetuspto-grants-1997_02
ORD IDord-fbcc31e750b74cf6992e80d619491b6f
Source noteuspto-grants-1997_02