Isoamylamine → HCID 86750387, compound

HRID 1451759Notes

Reaction equation

HRID 1451759 reaction equation
O[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH2:15]([NH2:20])[CH2:16][CH:17]([CH3:19])[CH3:18]>>[CH3:18][CH:17]([CH3:19])[CH2:16][CH2:15][NH:20][C:4]1[C:3]([N+:12]([O-:14])=[O:13])=[CH:2][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=1

Participants

3

Reactant 2

HCID 7894IsoamylamineHCID 178526762HCID 178526762, compound

Product 1

HCID 86750387HCID 86750387, compound

Procedure

Using the general method of Example 41, 4-hydroxy-3-nitroquinoline (19 g, 0.10 mole) was chlorinated and then reacted with isoamylamine (10.5 g, 0.12 mole) to provide the crude product as a yellow solid. This solid was recrystallized from hexane to provide the desired product as a solid, m.p. 99°-100° C. Analysis: Calculated: % C, 64.8; % H, 6.6; % N, 16.2; Found: % C, 64.8; % H, 6.6; % N, 16.1.

Workup

  1. customto provide the crude product as a yellow solid
  2. customThis solid was recrystallized from hexane

Sources & evidence

ORD record
ord-98fe857fdca64cb08584699cf65f7907
Source dataset
uspto-grants-1997_02
Patent number
US05605899

Reaction notes

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