HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propyl isocyanate → HCID 19972837, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propyl isocyanate | HCID 61033 | — |
| Reactant | 6-(2-amino-indan-5-yl)-4,5-dihydropyridazin-3(2H)-one | HCID 14071499 | — |
| Solvent | 2-Methoxyethanol | HCID 8019 | — |
| Product | HCID 19972837 | HCID 19972837 | 69.8% |
Reaction Steps
Propyl isocyanate (2.38 g) was added dropwise to 5.13 g of 2-amino-5-[4,5-dihydropyridazin-3(2H)-on-6-yl]indane suspended in 60 ml of 2-methoxyethanol. The mixture was stirred at room temperature for 10 minutes. Crystals precipitated were collected by filtration and recrystallized from methanol-acetonitrile to obtain 4.91 g of 2-(propylcarbamoyl)amino-5-[4,5-dihydropyridazin-3(2H)-on-6-yl]indane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05605901 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-c8738fe4aa8b4ba1a4b00aad24f73a6e |
| Source note | uspto-grants-1997_02 |