HCID 2779977, compound → HCID 10791746, compound

Participants

Reaction Steps

By the procedure described in Example 43, this compound was prepared from 5-(Pyridine-2-sulfonyl)-thiazolidine-2,4-dione of formula (V).Example 19 and [3-(3,5-bis(trifluoromethyl)phenyl)-prop-2-ynyl]-bromide of formula (IX), Example 31: mp 150°-152° C.: NMR (DMSO, d 6): δ8.79 (d, J=4.4 Hz, 1H, pyH), 8.16 (dr, J=1.6, 7.9 Hz, 1H, pyH), 8.11 (s, 1H, ArH), 8.05 (d, J=7.9 Hz, 1H, pyH), 7.94 (s, 2H, ArH), 7.9 (dd, J=4.9, 7.3 Hz, 1H, ArH), 3.87 (d, J=17.2 Hz, 1H, CH2), 3.71 (d, J=17.2 Hz, 1H, CH2); MS(CI): 509 (MI+1, 100%), 367 (32%), 366 (352%), 287 (35%), 194 (25%), 194 (20%); Anal. Calc. for C19H10F6N2O4S2 : C, 44.89; H, 1.98; N, 5.51; Found: C, 42.80; H, 2.09; N, 5.77.

Provenance & Evidence