HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-bromo-3-ethyl-5-nitroBenzene → 3-Bromo-5-ethylaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-bromo-3-ethyl-5-nitroBenzene | HCID 18929870 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Bromo-5-ethylaniline | HCID 18929899 | — |
Reaction Steps
Dissolve 3-bromo-5-ethylnitrobenzene (6.21g, 27mmol) in acetic acid (40mL) and ethanol (30mL) and treat with iron powder (2.7g). Reflux for 3 hours, filter through Celite and evaporate the solvent in vacuo. Purify by silica gel chromatography to give 3-bromo-5-ethylaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05606063 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-b46620aeb06f4cf682d50726ac488bb8 |
| Source note | uspto-grants-1997_02 |