HRID1452051

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID18929870

未命名化合物

PRODUCTS

生成物

HCID18929899

3-Bromo-5-ethylaniline

C8H10BrN

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23925

Iron

溶剂HCID176

Acetic Acid

C2H4O2

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Dissolve 3-bromo-5-ethylnitrobenzene (6.21g, 27mmol) in acetic acid (40mL) and ethanol (30mL) and treat with iron powder (2.7g). Reflux for 3 hours, filter through Celite and evaporate the solvent in vacuo. Purify by silica gel chromatography to give 3-bromo-5-ethylaniline.

WORKUP

后处理

temperatureReflux for 3 hours
filtrationfilter through Celite
customevaporate the solvent in vacuo
customPurify by silica gel chromatography