Hydrogen Peroxide → HCID 19972635, compound

HRID 1452289Notes

Reaction equation

HRID 1452289 reaction equation
[OH:1]O.[Cl:3][CH2:4][CH2:5][S:6][CH2:7][C:8]1[C:17]2[O:16][C:15]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[C:14]([CH3:24])[C:13](=[O:25])[C:12]=2[CH:11]=[CH:10][CH:9]=1.O>C(O)(=O)C>[Cl:3][CH2:4][CH2:5][S:6]([CH2:7][C:8]1[C:17]2[O:16][C:15]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[C:14]([CH3:24])[C:13](=[O:25])[C:12]=2[CH:11]=[CH:10][CH:9]=1)=[O:1]

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 962WaterHCID 19972533HCID 19972533, compound

Product 1

HCID 19972635HCID 19972635, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

36 ml of aqueous 30% hydrogen peroxide was quickly added dropwise at 10° C. to a solution of 12 g of Intermediate XXI in 84 ml of glacial acetic acid. The reaction mixture was stirred for 4 hours at ambient temperature, and then poured into 220 ml of water. The title compound was collected by suction filtration, washed with water and desiccated. Yield 12.4 g, m.p. 142°-145° C. (methanol).

Workup

  1. filtrationThe title compound was collected by suction filtration
  2. washwashed with water

Sources & evidence

ORD record
ord-2015d672ea944f04b83cc2a2326c615b
Source dataset
uspto-grants-1997_02
Patent number
US05605896

Reaction notes

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