Dichloromethane → HCID 19972557, compound

HRID 1452315Notes

Reaction equation

HRID 1452315 reaction equation
[NH2:1][CH2:2][C:3]1[C:12]2[O:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)=[C:9]([CH3:19])[C:8](=[O:20])[C:7]=2[CH:6]=[CH:5][CH:4]=1.Cl[CH2:22][CH2:23][S:24](Cl)(=[O:26])=[O:25].ClCCl>C(N(CC)CC)C>[CH:23]([S:24]([NH:1][CH2:2][C:3]1[C:12]2[O:11][C:10]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)=[C:9]([CH3:19])[C:8](=[O:20])[C:7]=2[CH:6]=[CH:5][CH:4]=1)(=[O:26])=[O:25])=[CH2:22]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 15385Ethanesulfonylchloride, 2-chloro-HCID 19972800HCID 19972800, compound

Product 1

HCID 19972557HCID 19972557, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

This compound can be prepared by reacting Intermediate XXIV with 2-chloroethylsulfonylchloride in an halogenated solvent (e.g., dichloromethane) in presence of triethylamine at 0°-40° C., according to A. A. Goldberg, Jr., J. Chem. Soc., 464 (1945).

Workup

  1. customThis compound can be prepared
  2. customat 0°-40° C.

Sources & evidence

ORD record
ord-96fc494f1f6749df952facf6bbbcd0c5
Source dataset
uspto-grants-1997_02
Patent number
US05605896

Reaction notes

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