HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86598351, compound → (5R)-3-[4-(1,1-Dioxo-3,6-dihydro-2H-thiopyran-4-yl)-3,5-difluorophenyl]-5-[(5-propyl-2H-tetrazol-2-yl)methyl]oxazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86598351 | HCID 86598351 | — |
| Reactant | HCID 178440452 | HCID 178440452 | — |
| Product | (5R)-3-[4-(1,1-Dioxo-3,6-dihydro-2H-thiopyran-4-yl)-3,5-difluorophenyl]-5-[(5-propyl-2H-tetrazol-2-yl)methyl]oxazolidin-2-one | HCID 10026918 | — |
Reaction Steps
This compound was prepared from 5-propyl-1H-tetrazole (0.187 g, 1.67 mmol) and (5R)-3-[4-(1,1-dioxo-3,6-dihydro-2H-thiopyran-4-yl)-3,5-difluorophenyl]-5-(hydroxymethyl)oxazolidin-2-one (WO 01/81350 A1) (0.30 g, 0.84 mmol) as described for Example 29. The title compound was obtained as a colourless solid (0.25 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07473699B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-62bccf8440744339a12227773ac1610d |
| Source note | uspto-grants-2009_01 |