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HRID1452598

反应详情

EQUATION

反应方程式

HRID 1452598 的结构方程式

REACTANTS

反应物

3
结构：C[Si](C)(C)[N-][Si](C)(C)C.[Li+]
HCID2733832

Lithium Hexamethyldisilazide

C6H18LiNSi2

结构：CSc1cn(-c2ccc(NC(=O)OCc3ccccc3)cc2F)nn1
HCID57526960

未命名化合物

2 次

结构：Cc1ncn(-c2ccc(N3C[C@H](CO)OC3=O)cc2F)n1
HCID57526987

未命名化合物

PRODUCTS

生成物

1
结构：CSc1cn(-c2ccc(N3C[C@H](CO)OC3=O)cc2F)nn1
HCID57526965

未命名化合物

PROCEDURE

实验过程

[3-Fluoro-4-[4-(methylthio)-1H-1,2,3-triazol-1-yl]phenyl] carbamic acid benzyl ester (Intermediate 49) (27.4 g, 76.5 mmol), LiHMDS (1M in THF, 91 ml) and R-(−)-glycidyl butyrate (11.5 g, 79.7 mmol) were reacted following the procedure for Intermediate 25 to give the crude title compound (19.4 g), which was used without further purification.