Lithium Hydroxide → HCID 86604233, compound

Participants

Reaction Steps

20.2 mg (0.04 mmol) of 4-{(S)-2-[2-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenoxy]-3-phenyl-propoxy}-benzoic acid (example 36) in 3 mL of THF were treated with 1 mg (0.04 mmol) of lithium hydroxide. The solvent was evaporated to give 21 mg (quantitative) of lithium 4-{(S)-2-[2-methyl-4-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenoxy]-3-phenyl-propoxy}-benzoate as a light yellow oil, MS: 527 (M−H)−.

Provenance & Evidence