2-Bromopyridine → 1-Cyclopentyl-3-[4-(3,5-dimethyl-isoxazol-4-yl)-phenyl]-propan-1-one

HRID 1453254Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([CH3:14])=[N:10][O:11][C:12]=2[CH3:13])=[CH:4][CH:3]=1.Br[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18]N=1>>[CH:16]1([C:12](=[O:11])[CH2:8][CH2:5][C:2]2[CH:7]=[CH:6][C:5]([C:8]3[C:9]([CH3:14])=[N:10][O:11][C:12]=3[CH3:13])=[CH:4][CH:3]=2)[CH2:21][CH2:20][CH2:19][CH2:18]1

Participants

Reactant 2

HCID 79732-Bromopyridine

HCID 103324224-(4-Bromo-phenyl)-3,5-dimethyl-isoxazole

Product 1

HCID 587624701-Cyclopentyl-3-[4-(3,5-dimethyl-isoxazol-4-yl)-phenyl]-propan-1-one

Procedure

The title compound was prepared as described in Step 1 of Example A(82), where 4-(4-Bromo-phenyl)-3,5-dimethyl-isoxazole from Step 1 of Example A(18), was substituted for 2-Bromopyridine.

Sources & evidence

ORD record: ord-a375ae6c82d34bc0a4b44dcfe50aa30a
Source dataset: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07473790B2

Reaction notes

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