2-Methylcyclohexylamine → 3-(2-Methoxy-phenyl)-N-(2-methyl-cyclohexyl)-acrylamide
Reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([OH:13])=O.[CH3:14][CH:15]1[CH2:20][CH2:19][CH2:18][CH2:17][CH:16]1[NH2:21]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[CH:10][C:11]([NH:21][CH:16]1[CH2:17][CH2:18][CH2:19][CH2:20][CH:15]1[CH3:14])=[O:13]Participants
3
Procedure
Prepared in a similar manner as described in example 4 from 3-(2-methoxy-phenyl)-acrylic acid and 2-methyl-cyclohexylamine. MS (M+H, 274.2).
Workup
- customPrepared in a similar manner
Sources & evidence
- ORD record
- ord-81e8b6f237144b94863e71601a98f3d8
- Source dataset
- uspto-grants-2009_01
- Patent number
- US07476399B2
Reaction notes
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