Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 178478376 | HCID 178478376 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178483054 | HCID 178483054 | — |
Reaction Steps
300 mg of product obtained in stage 1 above are mixed with 3 ml of DMF (dimethylformamide) and 0.17 ml (1.1 equivalents) of TEA (triethylamine). The mixture is heated at 90° C. for 2 hours. The precipitate is filtered off. Purification is carried out by chromatography on silica with a CH2Cl2-MeOH—NH4OH: 90-9-9 mixture for eluent. 298 mg of expected product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07476670B2 |
|---|
| Source dataset | uspto-grants-2009_01 |
|---|
| ORD ID | ord-4cacf908f01646c8ab84931e133ad2d4 |
|---|
| Source note | uspto-grants-2009_01 |
|---|
