Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methylindoline | HCID 23305 | — |
| Reactant | 2,6-Dichloropurine | HCID 5324412 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 178421929 | HCID 178421929 | 61.3% |
Reaction Steps
The same procedure as in stage 1 of Example 1 is carried out, mixing 189 mg of 2,6-dichloropurine, 5 ml of butanol and 0.16 g of 2-methylindoline. The mixture is heated at 130° C. for approximately 1 hour and allowed to return to ambient temperature. Partial drying is carried out, followed by washing with isopropanol. The product is dried and 174 mg of expected product are thus obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07476670B2 |
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| Source dataset | uspto-grants-2009_01 |
|---|
| ORD ID | ord-a3717b33c725487b9848ed040a17d8a4 |
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| Source note | uspto-grants-2009_01 |
|---|
