HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloropurine → HCID 178506067, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloropurine | HCID 5324412 | — |
| Reactant | 6-(Trifluoromethyl)indoline | HCID 10176437 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 178506067 | HCID 178506067 | 92.4% |
Reaction Steps
756 mg of 2,6-dichloropurine, 8 ml of butanol and 897 mg of 6-(trifluoromethyl)indoline are mixed and brought to a temperature of 90° C. for approximately 23 hours. The mixture is allowed to return to ambient temperature. Partial drying, washing with ethyl ether and drying under vacuum at 50° C. are carried out, and 1.256 g of expected product are obtained, in the form of beige crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07476670B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-7441ed4852aa4a509e750a4802b3e303 |
| Source note | uspto-grants-2009_01 |