Dimethyl Sulfate → HCID 86602101, compound

HRID 1453658Notes

Reaction equation

HRID 1453658 reaction equation
[C:1]1(=[O:8])[NH:7][CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH3:9][O:10][S:11]([O:14]C)(=[O:13])=[O:12]>>[CH3:9][O:8][C:1]1[CH2:2][CH2:3][O:4][CH2:5][CH2:6][N:7]=1.[CH3:9][O:10][S:11]([O-:14])(=[O:13])=[O:12]

Participants

3

Reactant 2

HCID 6497Dimethyl SulfateHCID 70230201,4-Oxazepan-5-one

Product 1

HCID 86602101HCID 86602101, compound

Procedure

3.50 g (30.4 mmol) 4-oxacaprolactam are heated to 55° C. in 3.90 ml (41.1 mmol) dimethylsulphate with stirring for 19 h. Then the mixture is evaporated down i. vac., and the residue is taken up twice in toluene and dichloromethane and completely concentrated by evaporation. The residue is further reacted directly.

Workup

  1. customThen the mixture is evaporated down i
  2. concentrationdichloromethane and completely concentrated by evaporation
  3. customThe residue is further reacted directly

Sources & evidence

ORD record
ord-a8508c5393f4472796a33eb6ed6b477d
Source dataset
uspto-grants-2009_01
Patent number
US07476663B2

Reaction notes

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