Thionyl Chloride → HCID 47153347, compound

HRID 1453660Notes

Reaction equation

HRID 1453660 reaction equation
Cl.[NH2:2][C:3]1([C:8]([O:10][CH3:11])=[O:9])[CH2:7][CH2:6][CH2:5][CH2:4]1.[Br:12][C:13]1[S:17][C:16]([C:18](O)=[O:19])=[CH:15][CH:14]=1.S(Cl)(Cl)=O>ClCCl>[Br:12][C:13]1[S:17][C:16]([C:18]([NH:2][C:3]2([C:8]([O:10][CH3:11])=[O:9])[CH2:7][CH2:6][CH2:5][CH2:4]2)=[O:19])=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 24386Thionyl ChlorideHCID 3491155-Bromothiophene-2-carboxylic acidHCID 11513856Methyl 1-amino-1-cyclopentanecarboxylate, HCl

Product 1

HCID 47153347HCID 47153347, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 37a from methyl 1-amino-cyclopentane-1-carboxylate hydrochloride and 5-bromo-thiophene-2-carboxylic acid with thionyl chloride in dichloromethane with TEA.

Sources & evidence

ORD record
ord-871d2aa36fbd423ba9e22663d5198bfd
Source dataset
uspto-grants-2009_01
Patent number
US07476663B2

Reaction notes

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