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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1453660Generated: October 31, 2026

Thionyl Chloride → HCID 47153347, compound

https://huagongshe.com/reaction/1453660

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReactantMethyl 1-amino-1-cyclopentanecarboxylate, HClHCID 11513856—
SolventDichloromethaneHCID 6344—
ProductHCID 47153347HCID 47153347—

Reaction Steps

Prepared analogously to Example 37a from methyl 1-amino-cyclopentane-1-carboxylate hydrochloride and 5-bromo-thiophene-2-carboxylic acid with thionyl chloride in dichloromethane with TEA.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07476663B2
Source datasetuspto-grants-2009_01
ORD IDord-871d2aa36fbd423ba9e22663d5198bfd
Source noteuspto-grants-2009_01