2-Methylindole → HCID 67316116, compound

HRID 1453682Notes

Reaction equation

HRID 1453682 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.Cl[C:12]1[C:16]2[CH:17]=[CH:18][C:19]([F:21])=[CH:20][C:15]=2[S:14](=[O:23])(=[O:22])[N:13]=1>>[F:21][C:19]1[CH:18]=[CH:17][C:16]2[C:12]([C:10]3[C:9]4[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=4)[NH:3][C:2]=3[CH3:1])=[N:13][S:14](=[O:23])(=[O:22])[C:15]=2[CH:20]=1

Participants

3

Reactant 2

HCID 72242-MethylindoleHCID 20434230HCID 20434230, compound

Product 1

HCID 67316116HCID 67316116, compound

Procedure

The sub-title compound was prepared as described for example 1, step b) using 2-methyl indole and the product from step b). The product did not crystallize upon quenching, and was instead purified by partitioning between DCM and water.

Workup

  1. customThe product did not crystallize
  2. customupon quenching
  3. customwas instead purified
  4. customby partitioning between DCM and water

Sources & evidence

ORD record
ord-b7f2731ea8784b3d8c8ae5a9f4f43916
Source dataset
uspto-grants-2009_01
Patent number
US07476667B2

Reaction notes

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