HCID 86605571, compound → 844503-06-6

HRID 1453957Notes

Reaction equation

HRID 1453957 reaction equation
[N:1]([CH2:4][CH2:5][C:6]1[C:7]([N+:12]([O-])=O)=[N:8][CH:9]=[CH:10][CH:11]=1)=[N+]=[N-].[H][H]>CO.[Pd]>[NH2:1][CH2:4][CH2:5][C:6]1[C:7]([NH2:12])=[N:8][CH:9]=[CH:10][CH:11]=1

Participants

5

Reactant 2

HCID 86605571HCID 86605571, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 54105929844503-06-6Yield 90.7%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A solution of 3-(2-azidoethyl)-2-nitropyridine (0.190 g, 0.98 mmol) in methanol (5 mL) was stirred at 20° C. with 10% palladium on carbon (50 mg) under 1 atm hydrogen for 96 h. The mixture was filtered through celite and the filtrate concentrated to give the title compound (0.122 g).

Workup

  1. filtrationThe mixture was filtered through celite
  2. concentrationthe filtrate concentrated

Sources & evidence

ORD record
ord-9c891b052f434b9886484b683474ae87
Source dataset
uspto-grants-2009_01
Patent number
US07476665B2

Reaction notes

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