Tetrahydrofuran → 3-Methoxy-4-(4-triisopropylsilanyloxy-piperidin-1-yl)-phenylamine

HRID 145407Notes

Reaction equation

HRID 145407 reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:1][O:2][c:3]1[c:4]([N:12]2[CH2:13][CH2:14][CH:15]([O:18][Si:19]([CH:20]([CH3:21])[CH3:22])([CH:23]([CH3:24])[CH3:25])[CH:26]([CH3:27])[CH3:28])[CH2:16][CH2:17]2)[cH:5][cH:6][c:7]([N+:9]([O-:10])=[O:11])[cH:8]1>>[CH3:1][O:2][c:3]1[c:4]([N:12]2[CH2:13][CH2:14][CH:15]([O:18][Si:19]([CH:20]([CH3:21])[CH3:22])([CH:23]([CH3:24])[CH3:25])[CH:26]([CH3:27])[CH3:28])[CH2:16][CH2:17]2)[cH:5][cH:6][c:7]([NH2:9])[cH:8]1

Participants

3

Reactant 2

HCID 8028TetrahydrofuranHCID 575017001-(2-Methoxy-4-nitro-phenyl)-4-triisopropylsilanyloxy-piperidine

Product 1

HCID 575017063-Methoxy-4-(4-triisopropylsilanyloxy-piperidin-1-yl)-phenylamine

Sources & evidence

ORD record
ord-d09fe2b29ddc4167b08b2fe5d15a79fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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