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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454323Generated: October 25, 2026

Ketamine → Esmolol

https://huagongshe.com/reaction/1454323

Reaction equation

Participants

RoleNameHCIDCharge
ReactantKetamineHCID 3821—
ReactantMetoprololHCID 4171—
ReactantPropranololHCID 4946—
ReactantXylazineHCID 5707—
ReactantAcepromazine MaleateHCID 6420038—
ReactantGs-9667HCID 11561692—
SolventDimethyl SulfoxideHCID 679—
ProductEsmololHCID 59768—

Reaction Steps

Rats (Sprague Dawley) weighing 300-400 gms were purchased from Simonsen laboratories. CVT-3619 was dissolved in DMSO and further diluted in saline. CVT-510 was dissolved in saline. Ketamine was purchased from Fort Dodge Animal Health, Xylazine from Bayer and Acepromazine Maleate from Fermenta Animal Health Co. Metoprolol and propranolol were purchased from SIGMA. Esmolol was obtained from a local pharmacy.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07479485B2
Source datasetuspto-grants-2009_01
ORD IDord-4b75149209604688b19e1400bc412ecb
Source noteuspto-grants-2009_01