O-Xylene → HCID 68818706, compound

HRID 1454423Notes

Reaction equation

HRID 1454423 reaction equation
[C:1]([O:6][C:7](=[O:11])[CH:8]([CH3:10])[CH3:9])(=O)[CH:2]([CH3:4])C.[C:12]1([CH3:19])[C:13]([CH3:18])=[CH:14][CH:15]=[CH:16][CH:17]=1>>[C:7]([O:6][C:1]1[CH2:2][CH2:4][CH2:19][CH2:12][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:18][CH2:16][CH2:17][C@@H:12]([CH3:19])[CH:13]=1)(=[O:11])[CH:8]([CH3:9])[CH3:10]

Participants

3

Reactant 2

HCID 7237O-XyleneHCID 7346Isobutyric anhydride

Product 1

HCID 68818706HCID 68818706, compoundYield 81%

Procedure

A crude product was prepared under the same condition as that in Example 6 except that isobutanoic anhydride was used instead of n-butanoic anhydride and xylene was used in an amount of 14 g, and was purified and isolated by silica gel column chromatography to give 2.5 g (8.14 mmol) of the title compound (R)-3-methyl-1-cyclopentadecenyl isobutyrate (yield: 81%). Gas chromatographic analysis thereof gave E/Z=1.4/98.6.

Workup

  1. customwas purified
  2. customisolated by silica gel column chromatography

Sources & evidence

ORD record
ord-dc983ba44e0d4d46ba2e5e588d7a78a7
Source dataset
uspto-grants-2009_01
Patent number
US07479574B2

Reaction notes

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