反应详情

In a 250 mL flask, TFA (24.7 mL; 322.8 mmol) and acetyl chloride (18.34 mL; 258.23 mmol) were added in one portion into 2-(4-bromophenyl)-1-(4-chlorophenyl) ethanone (Vd) (10.0 g; 32.30 mmol) at RT. Protocol and work-up was then similar with those described above. The title compound (m=7.89 g) was obtained in a 74.5% yield. Melting point: 108° C.