Benzenesulfonamide → HCID 86607707, compound

HRID 1454522Notes

Reaction equation

Br[C:2]1[CH:3]=[C:4]([S:12]([NH:15][CH2:16][CH2:17][CH2:18][CH3:19])(=[O:14])=[O:13])[CH:5]=[C:6]([CH:10]=[O:11])[C:7]=1[O:8][CH3:9].[C:20]1([S:26]([NH2:29])(=[O:28])=[O:27])[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:16]([NH:15][S:12]([C:4]1[CH:3]=[C:2]([C:22]2[CH:23]=[CH:24][CH:25]=[C:20]([S:26]([NH:29][C:6]([CH3:10])([CH3:7])[CH3:5])(=[O:28])=[O:27])[CH:21]=2)[C:7]([O:8][CH3:9])=[C:6]([CH:10]=[O:11])[CH:5]=1)(=[O:14])=[O:13])[CH2:17][CH2:18][CH3:19]

Participants

Reactant 2

HCID 7370Benzenesulfonamide

HCID 866077083-bromo-N-butyl-5-formyl-4-methoxy-benzenesulfonamide

Product 1

HCID 86607707HCID 86607707, compoundYield 178.3%

Procedure

Proceeding as in Reference 19, but substituting 3-bromo-N-butyl-5-formyl-4-methoxy-benzenesulfonamide (0.65 g, 1.72 mmol) and N-tert-butyl-3-4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzenesulfonamide (0.64 g, 1.90 mmol, 1.1 eq.), gave N-butyl-N′-tert-butyl-5-formyl-6-methoxy-biphenyl-3,3′-disulfonamide (0.74 g) as on orange oil.

Sources & evidence

ORD record: ord-3bfc1b0076cf477b8753c98ea1cb10f4
Source dataset: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07479502B2

Reaction notes

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