Water → HCID 86620812, compound

HRID 1454752Notes

Reaction equation

HRID 1454752 reaction equation
[K].[C:2]([O:6][C:7](=[O:13])[CH:8]([C:11]#[N:12])[CH:9]=[O:10])([CH3:5])([CH3:4])[CH3:3].[Cl-].[C:15]1([S+:21]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.O>>[C:28]1([S+:21]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1.[C:2]([O:6][C:7](=[O:13])[CH:8]([C:11]#[N:12])[CH:9]=[O:10])([CH3:5])([CH3:3])[CH3:4]

Participants

5

Reactant 4

HCID 962WaterHCID 61343Triphenylsulfonium chlorideHCID 5462222PotassiumHCID 86620813HCID 86620813, compound

Product 1

HCID 86620812HCID 86620812, compoundYield 79%

Procedure

COMP CD-8 was prepared similar to COMP CD-7 at 79% yield from potassium salt of 3-oxo-2-cyanopropanoic acid t-butyl ester (2.07 g, 10 mmol) and 50% solution of triphenylsulfonium chloride in water (5.96 g, 10 mmol) as a yellow color, light weight (fluffy) crystalline material.

Sources & evidence

ORD record
ord-038bffab496c45838222c722c8aba08d
Source dataset
uspto-grants-2009_01
Patent number
US07482113B2

Reaction notes

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