HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 6-(4-Fluoro-benzyloxymethyl)-pyridin-2-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-[6-(4-Fluoro-benzyloxymethyl)-pyridin-2-yl]-2,2-dimethyl-propionamide | HCID 68842438 | — |
| Product | 6-(4-Fluoro-benzyloxymethyl)-pyridin-2-ylamine | HCID 68845140 | — |
Reaction Steps
This material was prepared in analogy to example 86 step B] from N-[6-(4-Fluoro-benzyloxymethyl)-pyridin-2-yl]-2,2-dimethyl-propionamide (0.825 g) and 3M aqueous NaOH (4.35 mL) as a yellow oil (0.596 g). MS (ESI): 233.1 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482341B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-c074a530cc194ec2a2886d5018e99a38 |
| Source note | uspto-grants-2009_01 |