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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454838Generated: October 30, 2026

Sodium Hydroxide → 5-Cyclopropylmethoxymethyl-pyridin-2-ylamine

https://huagongshe.com/reaction/1454838

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantN-(5-Cyclopropylmethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamideHCID 68842953—
Product5-Cyclopropylmethoxymethyl-pyridin-2-ylamineHCID 62194299—

Reaction Steps

This material was prepared in analogy to example 86 step B] from N-(5-cyclopropylmethoxymethyl-pyridin-2-yl)-2,2-dimethyl-propionamide (0.87 g) and 3M aqueous NaOH (5.54 mL) as a yellow solid (0.527 g). MS (ESI): 179.1 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07482341B2
Source datasetuspto-grants-2009_01
ORD IDord-fc2b903cbe9447549cee38f323843824
Source noteuspto-grants-2009_01