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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454846Generated: October 25, 2026

2,5-Difluorobenzenesulfonyl chloride → N-(5-Cyclopropylmethoxymethyl-6-methyl-pyridin-2-yl)-2,5-difluoro-benzenesulfonamide

https://huagongshe.com/reaction/1454846

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-Difluorobenzenesulfonyl chlorideHCID 2736911—
Reactant5-Cyclopropylmethoxymethyl-6-methyl-pyridin-2-ylamineHCID 68843148—
ProductN-(5-Cyclopropylmethoxymethyl-6-methyl-pyridin-2-yl)-2,5-difluoro-benzenesulfonamideHCID 68843870—

Reaction Steps

This material was prepared in analogy to example 1 from 5-cyclopropylmethoxymethyl-6-methyl-pyridin-2-ylamine (0.053 g) and 2,5-difluoro-benzenesulfonyl chloride (0.059 g) as a light yellow solid (0.063 g). MS (ESI−): 367.0 ([M−H]−)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07482341B2
Source datasetuspto-grants-2009_01
ORD IDord-fc221f7f30f246059ca3ce29b368c3ab
Source noteuspto-grants-2009_01