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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454857Generated: October 26, 2026

Sodium Hydroxide → 5-Ethoxymethyl-6-methyl-pyridin-2-ylamine

https://huagongshe.com/reaction/1454857

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantN-(5-Ethoxymethyl-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamideHCID 68840796—
Product5-Ethoxymethyl-6-methyl-pyridin-2-ylamineHCID 68840827—

Reaction Steps

This material was prepared in analogy to example 86 step B] from N-(5-ethoxymethyl-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide (0.32 g) and 3M aqueous NaOH (2.62 mL) as a yellow oil (0.28 g) that was used directly in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07482341B2
Source datasetuspto-grants-2009_01
ORD IDord-260856e1cf7a460982668da25a610f54
Source noteuspto-grants-2009_01