3-Chloro-2-methylbenzenesulfonyl chloride → 3-Chloro-N-(5-ethoxymethyl-6-methyl-pyridin-2-yl)-2-methyl-benzenesulfonamide

HRID 1454862Notes

Reaction equation

HRID 1454862 reaction equation
[CH2:1]([O:3][CH2:4][C:5]1[CH:6]=[CH:7][C:8]([NH2:12])=[N:9][C:10]=1[CH3:11])[CH3:2].[Cl:13][C:14]1[C:15]([CH3:24])=[C:16]([S:20](Cl)(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1>>[Cl:13][C:14]1[C:15]([CH3:24])=[C:16]([S:20]([NH:12][C:8]2[CH:7]=[CH:6][C:5]([CH2:4][O:3][CH2:1][CH3:2])=[C:10]([CH3:11])[N:9]=2)(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 5227343-Chloro-2-methylbenzenesulfonyl chlorideHCID 688408275-Ethoxymethyl-6-methyl-pyridin-2-ylamine

Product 1

HCID 688465683-Chloro-N-(5-ethoxymethyl-6-methyl-pyridin-2-yl)-2-methyl-benzenesulfonamide

Procedure

This material was prepared in analogy to example 1 from 5-ethoxymethyl-6-methyl-pyridin-2-ylamine (0.066 g) and 3-chloro-2-methyl-benzenesulfonyl chloride (0.099 g) as an off-white solid (0.08 g). MS (ESI−): 351.3 ([M−H]−)

Sources & evidence

ORD record
ord-8d9a06fcc4ab4cbab731ddc2cda6a67b
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Reaction notes

Loading…