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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454864Generated: October 30, 2026

3-(Trifluoromethyl)benzenesulfonyl chloride → N-(5-Cyclopropylmethoxymethyl-pyridin-2-yl)-3-trifluoromethyl-benzenesulfonamide

https://huagongshe.com/reaction/1454864

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethyl)benzenesulfonyl chlorideHCID 2733250—
Reactant5-Cyclopropylmethoxymethyl-pyridin-2-ylamineHCID 62194299—
ProductN-(5-Cyclopropylmethoxymethyl-pyridin-2-yl)-3-trifluoromethyl-benzenesulfonamideHCID 68845578—

Reaction Steps

This material was prepared in analogy to example 1 from 5-cyclopropylmethoxymethyl-pyridin-2-ylamine (0.051 g) and 3-(trifluromethyl)-benzenesulfonyl chloride (0.077 g) as a crystalline white solid (0.062 g). MS (ESI−): 385.0 ([M−H]−)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07482341B2
Source datasetuspto-grants-2009_01
ORD IDord-8bb9be0363f74f3c98ff25d72a193e28
Source noteuspto-grants-2009_01