HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoroethyl bromide → N-[5-(2-Fluoro-ethoxymethyl)-6-methyl-pyridin-2-yl]-2,2-dimethyl-propionamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoroethyl bromide | HCID 12982 | — |
| Reactant | N-(5-Hydroxymethyl-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide | HCID 68844472 | — |
| Product | N-[5-(2-Fluoro-ethoxymethyl)-6-methyl-pyridin-2-yl]-2,2-dimethyl-propionamide | HCID 86604238 | — |
Reaction Steps
This material was prepared in analogy to example 86 step A] from N-(5-hydroxymethyl-6-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide (0.556 g, product of example 112 step B]) and 1-bromo-2-fluoro-ethane (0.475 g) as a light yellow gum (0.115 g). MS (ESI): 269.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482341B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-2a76463275cd47b4ab049ec8f2aa6112 |
| Source note | uspto-grants-2009_01 |