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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454888Generated: October 31, 2026

Sodium Hydroxide → 2-Pyridinamine, 6-[(3,3,3-trifluoropropoxy)methyl]-

https://huagongshe.com/reaction/1454888

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 68842009HCID 68842009—
Product2-Pyridinamine, 6-[(3,3,3-trifluoropropoxy)methyl]-HCID 68842615—

Reaction Steps

This material was prepared in analogy to example 86 step B] from 2,2-dimethyl-N-[6-(3,3,3-trifluoro-propoxymethyl)-pyridin-2-yl]-propionamide (0.2 g) and 3M aqueous NaOH (1.31 mL) as a brown oil (0.159 g). MS (ESI): 221.2 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07482341B2
Source datasetuspto-grants-2009_01
ORD IDord-8d37ae79b3ea4dfda75b8804b4af02cf
Source noteuspto-grants-2009_01