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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1454894Generated: October 26, 2026

Sodium Hydroxide → 6-(2-Cyclopropyl-ethoxymethyl)-pyridin-2-ylamine

https://huagongshe.com/reaction/1454894

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantN-[6-(2-cyclopropyl-ethoxymethyl)-pyridin-2-yl]-2,2-dimethyl-propionamideHCID 68842043—
Product6-(2-Cyclopropyl-ethoxymethyl)-pyridin-2-ylamineHCID 68842176—

Reaction Steps

This material was prepared in analogy to example 86 step B] from N-[6-(2-cyclopropyl-ethoxymethyl)-pyridin-2-yl]-2,2-dimethyl-propionamide (0.51 g) and 3M aqueous NaOH (3.7 mL) as a light yellow oil (0.39 g) that was used directly in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07482341B2
Source datasetuspto-grants-2009_01
ORD IDord-cfb8d46292dc43bfaad594fb05232523
Source noteuspto-grants-2009_01