HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride → n-[6-(2-Cyclopropyl-ethoxymethyl)-pyridin-2-yl]-4-fluoro-3-trifluoromethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-3-(trifluoromethyl)benzenesulfonyl Chloride | HCID 2737549 | — |
| Reactant | 6-(2-Cyclopropyl-ethoxymethyl)-pyridin-2-ylamine | HCID 68842176 | — |
| Product | n-[6-(2-Cyclopropyl-ethoxymethyl)-pyridin-2-yl]-4-fluoro-3-trifluoromethyl-benzenesulfonamide | HCID 68841680 | — |
Reaction Steps
This material was prepared in analogy to example 1 from 6-(2-cyclopropyl-ethoxymethyl)-pyridin-2-ylamine (0.08 g) and 4-fluoro-3-(trifluormethyl)-benzenesulfonyl chloride (0.12 g) as a light yellow gum (0.08 g). MS (ESI−): 417.0 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482341B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-0f4ffbb83dc44a8e910cd1be0b18d3e3 |
| Source note | uspto-grants-2009_01 |