反应详情

To a solution of 2,5-dibromopyridine (10 g) in THF was added Tetrakis (2.2 g) and 2,6-difluorobenzylzinc bromide (126 mL, 63 mmol). The reaction was heated to reflux until reaction was complete by TLC. The reaction was cooled to room temperature, filtered through celite, and concentrated in vacuo. The title compound was purified by silica gel (Hexanes/methylene chloride).

1. temperatureThe reaction was heated
2. temperatureto reflux until reaction
3. filtrationfiltered through celite
4. concentrationconcentrated in vacuo
5. customThe title compound was purified by silica gel (Hexanes/methylene chloride)