HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 7-[3-Amino-4-methylpiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid hydrochloride salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 7-[3-Amino-4-methylpiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid | HCID 18333190 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 7-[3-Amino-4-methylpiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid hydrochloride salt | HCID 68880127 | — |
Reaction Steps
A quantity of 0.20 g of 7-[3-amino-4-methylpiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid is suspended in 1.0 mL of ethanol. Its pH is adjusted to 2 with hydrogen chloride to obtain the desired product after the evaporation of solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482454B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-7a114be64c2b4976b7588448a0881350 |
| Source note | uspto-grants-2009_01 |