HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 7-[3-Aminopiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid dihydrochloride salt
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Nemonoxacin Impurity 77 | HCID 9863559 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 7-[3-Aminopiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid dihydrochloride salt | HCID 68882635 | — |
Reaction Steps
A quantity of 0.19 g of 7-[3-aminopiperidinyl]-1-cyclopropyl-1,4-dihydro-8-methoxy-4-oxo-quinoline-3-carboxylic acid is suspended in 1.0 mL of ethanol. The pH of the solution is adjusted to 2 with the addition of hydrogen chloride. The desired product is obtained by evaporation of the solvent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482454B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-77992d916ad5451fbbf8dbabbf7dbf29 |
| Source note | uspto-grants-2009_01 |