Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | HCID 57535470 | HCID 57535470 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 178480239 | HCID 178480239 | 99% |
Reaction Steps
A mixture of 4-(2-fluoro-5-iodobenzoyl)-1-methylpiperidine (4.20 g, 12.1 mmol), anhydrous NH2NH2 (30 mL), and DMSO (15 mL) was heated at 100° C. overnight, diluted with ice water and filtered. The filtercake was washed with water and dried in vacuo to provide the title compound (4.1 g, 99%), characterized by HNMR and mass spectral analyses.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07482461B2 |
|---|
| Source dataset | uspto-grants-2009_01 |
|---|
| ORD ID | ord-e960675e2f064c62bb1416663de01f5e |
|---|
| Source note | uspto-grants-2009_01 |
|---|
