HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3,5-Bis(trifluoromethyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3,5-Bis(trifluoromethyl)benzenesulphonyl chloride | HCID 520945 | — |
| Product | 3,5-Bis(trifluoromethyl)benzenesulfonamide | HCID 2783165 | — |
Reaction Steps
An aqueous solution of NH3 (32%) is added at room temperature to a solution of 3,5-bis-(trifluoromethyl)benzene-sulfonylchloride in EtAc. The mixture obtained is stirred and two phases obtained are separated, the organic layer obtained is washed with 1 N HCl and H2O, and dried. Solvent of the organic solution obtained is evaporated. 3,5-Bis-trifluoromethyl-benzene sulfonamide is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07482462B2 |
| Source dataset | uspto-grants-2009_01 |
| ORD ID | ord-d52345419b5f405a9507eafc24995853 |
| Source note | uspto-grants-2009_01 |