HCID 23436728, compound → HCID 53924006, compound

HRID 1455657Notes

Reaction equation

HRID 1455657 reaction equation
[CH3:1][Mg]Br.[Br:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11]1[CH:16]=[CH:15][C:14]([C:17](=[O:19])[CH3:18])=[CH:13][CH:12]=1>CCOC(C)=O>[Br:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[C:11]1[CH:16]=[CH:15][C:14]([C:17]([OH:19])([CH3:1])[CH3:18])=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 23436728HCID 23436728, compoundHCID 178418573HCID 178418573, compound

Product 1

HCID 53924006HCID 53924006, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Prepared according to the general procedure Cer-1 using methyl magnesium bromide and ketone from step 1 as starting material. Flash chromatography (Hex:EtOAc; 90:10) afforded the title compound.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b2008bf6a098462bb1160c41a73cbfb0
Source dataset
uspto-grants-2009_01
Patent number
US07482456B2

Reaction notes

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