Borane → N-(1-Boc-piperidin-3-ylmethyl)aniline

HRID 145569Notes

Reaction equation

HRID 145569 reaction equation
[BH3:23].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[c:1]1([NH:7][C:8](=[O:9])[CH:10]2[CH2:11][N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([NH:7][CH2:8][CH:10]2[CH2:11][N:12]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:13][CH2:14][CH2:15]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6331BoraneHCID 8028TetrahydrofuranHCID 181042161,1-Dimethylethyl 3-[(phenylamino)carbonyl]-1-piperidinecarboxylate

Product 1

HCID 12972131N-(1-Boc-piperidin-3-ylmethyl)aniline

Sources & evidence

ORD record
ord-18441bad866e4636840d56d5f4045e8d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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