反应详情

48 g (0.18 mol) of 3-(3-bromo-4-methoxyphenyl)propanoyl chloride are dissolved in 500 ml of dichloromethane. 72 g (0.54 mol) of aluminium chloride are added in small amounts. The reaction medium is stirred for 2 hours and then poured into water and the phases are separated by settling. The organic phase is dried (Na2SO4) and the solvent is evaporated off: (39.8 g). The product is triturated in ethanol, filtered off and dried (25 g; 63%)

1. customthe phases are separated
2. dry with materialThe organic phase is dried (Na2SO4)
3. customthe solvent is evaporated off
4. customThe product is triturated in ethanol
5. filtrationfiltered off
6. customdried (25 g; 63%)